• Viagra, Levitra and Cialis are Safe Not for Everyone

    Although drugs to eliminate erectile dysfunction (impotence) can help many people, not all men can safely take them. Viagra, Levitra and Cialis are contraindicated if you have:

    • heart problems, including recent heart attack, heart pain (cardiac angina) during sex, cardiac insufficiency, heart rhythm problems (arrhythmias);
    • uncontrolled high or low blood pressure (hypertension or hypotension);
    • blood stroke in the last six months;
    • retinal disorders, including NARP;
    • sickle cell anemia, leukemia and other health conditions, which can lead to the fact that erection will not weaken (priapism).

    (more…)

  • How to Maintain Your Body to Prevent Erectile Dysfunction

    Studies have noted that the chances of suffering from ED tend to increase with a rise in age. As a result, many men mistakenly believe that it is a part of the natural aging process and that they will be incapable of preventing it. However, that is far from the truth. It is certainly possible to prevent erectile dysfunction by maintaining your body. Doing so will also help you to avoid medicines like Viagra soft from My Canadian Pharmacy.

    Here are some of the ways you can keep your body functioning properly so that erectile dysfunction does not become an issue.

    Follow a Proper Diet

    Erections depend on a proper blood flow to the penile region. Therefore, you will find it more difficult to achieve erections if your heart or your cardiovascular system is not working properly. Now, the health of the cardiovascular system depends greatly on your diet.

    Diets that contain a lot of fat and sugar can impair your cardiovascular function. Bad diets can lead to a high cholesterol level which decreases the blood flow greatly. For these reasons, you need to ensure that your diet is the right one. Keep in mind that if a diet is bad for your heart then it can also end up causing erectile dysfunction.

    Viagra

    Reduce Your Weight

    Obesity is the leading cause for a number of health complications such as type 2 diabetes. Diabetes can damage nerves all over the body including the ones present in the penile region. If the nerves do not work properly, it becomes difficult for an erection to take place. The cardiovascular system is also affected by obesity. Due to these two reasons, you have to try and bring your weight under control.

    Exercise on a Regular Basis

    Research has shown that there are links between sedentary lifestyles and erectile dysfunction. Therefore, you should exercise regularly if you want to prevent ED. There are many exercises you can perform. However, aerobic exercises have the maximum benefit in the prevention of ED. Some aerobic exercises that you can perform are given below.Running

    • Running
    • Swimming
    • High-intensity interval workouts
    • Pylometrics
    • Indoor rowing

    It is important that you limit any exercises that put a lot of pressure on the perineum region. The region between the anus and the scrotum is known as the perineum. Excess pressure here can lead to erectile dysfunction. That is why you must not cycle excessively.

    Things to Avoid

    In order to keep your body completely fit, you must make sure that you avoid certain things. Otherwise, the chances of developing ED will rise significantly. Here are some of the things you must avoid.

    • Anabolic Steroids
    • Smoking
    • Excessive consumption of alcohol
    • Drug abuse
    • Penile injuries

    Generally, these tips will help you prevent ED from taking place. However, due to the wide range of causes, it is possible that you can start suffering from ED in spite of your best efforts. Instead of panicking, consult a doctor to check if drugs like Viagra soft can help in your treatment. Apart from Viagra, other ED drugs are also available at My Canadian Pharmacy.

  • The Potential Use of Type-5 Phosphodiesterase Inhibitors Viagra, Cialis, Levitra in Coronary Artery Bypass Graft Surgery: Mechanisms of Vasodilation Related to PDEs

    coronary artery bypass graftingType-5 phosphodiesterase (PDE5) is an enzyme with a predominant presence in the corpus cavernosum, vascular smooth muscle, and platelets. PDE5 inhibitors in conjunction with endogenous nitric oxide (NO) can produce potent relaxation of corpus cavernosal smooth muscle, which explains their popularity in the treatment of erectile dysfunction. Sildenafil citrate, levitra, and cialis are chemical agents that specifically inhibit PDE5, Among them, viagra has been the most well studied.

    Clinical trials have shown significant benefits of viagra in patients with pulmonary arterial hypertension. More recently, the endothelium-enhancing effects of viagra in preconditioning prior to ischemia/reperfusion in healthy human subjects has been demonstrated. Sildenafil has powerful effects in conduits that are useful in coronary artery bypass grafting (CABG), including the saphenous vein, and the coronary, mammary, and radial arteries.

    CABG has now matured to a point where the all-cause hospital mortality rate in low-risk patients is generally < 1%. The highest risk period is that immediately after operation, and the incremental number of risk factors positively correlates with higher mortality rates.- The use of auxiliary pharmacologic agents intraoperatively and/or perioperatively may help to modify risks, particularly in an aging patient population with increasing operative risks. Although there are currently no published clinical studies or trials investigating PDE5 inhibitors in this regard, accumulating evidence strongly suggests that they may be potential candidates for these roles: the reduction of vasospasm of the bypass graft, improvement in myocardial perfusion and coronary blood flow, and reduction of untoward events associated with platelet activation during cardiac surgery.

    (more…)

  • The Potential Use of Type-5 Phosphodiesterase Inhibitors Viagra, Cialis, Levitra in Coronary Artery Bypass Graft Surgery: Pulmonary Hypertension and Cardiopulmonary Bypass

    viagraIn addition to its responsiveness in the corpus cavernosum and coronary artery, PDE5 inhibitors also act selectively in the pulmonary vasculature, and patients with elevated pulmonary pressures appear to benefit significantly from its action even when administered orally. Published data have come primarily from the study of viagra.

    A randomized double-blind trial found that viagra was protective against acute hypoxia (11% inspired oxygen) in healthy human volunteers, almost completely reversing the raised pulmonary artery pressure. In a study of five consecutive patients with pulmonary hypertension, oral viagra (50 mg q8h) decreased pulmonary capillary wedge pressures, increased cardiac index, improved functional capacity, and led to a reduction of right ventricular mass measured by MRI. Systolic and diastolic pressures were found to be unchanged in these patients. In another similar study, oral viagra, 50 mg tid, for 3 months significantly reduced pulmonary artery pressure and pulmonary vascular resistance, increased cardiac output and exercise tolerance (measured by using the 6-min walk test), and improved quality of life. A larger, double-blind, placebo-controlled crossover trial of 22 patients confirmed similar benefits: significant improvement in exercise tolerance (+ 44% measured by treadmill exercise time), improved cardiac index, and reduced pulmonary artery systolic pressure. Patient symptoms were reported to be improved in the above studies.

    (more…)