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Upcoming Live Lecture Classes
New York, NY: June 21-26, 2008
New York, NY: September 27-October 2, 2008Miami, FL: May 30-June 4th, 2008
Pharmacology Course - (one day class)
New York, NY: June 29, 2008
New York, NY: October 5, 2008
Class Hours : 8:00 AM to 5:00 PM

Viagra, Levitra and Cialis are Safe Not for Everyone

Although drugs to eliminate erectile dysfunction (impotence) can help many people, not all men can safely take them. Viagra, Levitra and Cialis are contraindicated if you have:

  • heart problems, including recent heart attack, heart pain (cardiac angina) during sex, cardiac insufficiency, heart rhythm problems (arrhythmias);
  • uncontrolled high or low blood pressure (hypertension or hypotension);
  • blood stroke in the last six months;
  • retinal disorders, including NARP;
  • sickle cell anemia, leukemia and other health conditions, which can lead to the fact that erection will not weaken (priapism).

Causes of Erectile Dysfunction in Men

Sexual health of a man is an integral part of his life, which affects his psychoemotional state and general health. Any problems in sexual sphere can negatively affect both relationship with partner and entire social life of the person. Unfortunately, an increasing number of representatives of the stronger sex all over the world complain of decreased libido and weak erection, which makes it impossible to have a full sexual intercourse. And doctors more and more often diagnose «erectile dysfunction». In order to select adequate treatment for impotence it is necessary to identify reason for its appearance.

How to Maintain Your Body to Prevent Erectile Dysfunction

Studies have noted that the chances of suffering from ED tend to increase with a rise in age. As a result, many men mistakenly believe that it is a part of the natural aging process and that they will be incapable of preventing it. However, that is far from the truth. It is certainly possible to prevent erectile dysfunction by maintaining your body. Doing so will also help you to avoid medicines like Viagra soft from My Canadian Pharmacy.

Here are some of the ways you can keep your body functioning properly so that erectile dysfunction does not become an issue.

Follow a Proper Diet

Erections depend on a proper blood flow to the penile region. Therefore, you will find it more difficult to achieve erections if your heart or your cardiovascular system is not working properly. Now, the health of the cardiovascular system depends greatly on your diet.

Diets that contain a lot of fat and sugar can impair your cardiovascular function. Bad diets can lead to a high cholesterol level which decreases the blood flow greatly. For these reasons, you need to ensure that your diet is the right one. Keep in mind that if a diet is bad for your heart then it can also end up causing erectile dysfunction.

Viagra

Reduce Your Weight

Obesity is the leading cause for a number of health complications such as type 2 diabetes. Diabetes can damage nerves all over the body including the ones present in the penile region. If the nerves do not work properly, it becomes difficult for an erection to take place. The cardiovascular system is also affected by obesity. Due to these two reasons, you have to try and bring your weight under control.

Exercise on a Regular Basis

Research has shown that there are links between sedentary lifestyles and erectile dysfunction. Therefore, you should exercise regularly if you want to prevent ED. There are many exercises you can perform. However, aerobic exercises have the maximum benefit in the prevention of ED. Some aerobic exercises that you can perform are given below.Running

  • Running
  • Swimming
  • High-intensity interval workouts
  • Pylometrics
  • Indoor rowing

It is important that you limit any exercises that put a lot of pressure on the perineum region. The region between the anus and the scrotum is known as the perineum. Excess pressure here can lead to erectile dysfunction. That is why you must not cycle excessively.

Things to Avoid

In order to keep your body completely fit, you must make sure that you avoid certain things. Otherwise, the chances of developing ED will rise significantly. Here are some of the things you must avoid.

  • Anabolic Steroids
  • Smoking
  • Excessive consumption of alcohol
  • Drug abuse
  • Penile injuries

Generally, these tips will help you prevent ED from taking place. However, due to the wide range of causes, it is possible that you can start suffering from ED in spite of your best efforts. Instead of panicking, consult a doctor to check if drugs like Viagra soft can help in your treatment. Apart from Viagra, other ED drugs are also available at My Canadian Pharmacy.

Deliberations of Aerosolized Magnesium Sulfate for Acute Asthma

patients with acute asthmaThis systematic review attempted to synthesize the best available evidence for the use of inhaled MgSO4 in the treatment of patients with acute asthma. From six RCTs involving nearly 300 patients, the results of this review provide somewhat weak and conflicting conclusions. First, based on the available data, it appears that therapy with nebulized isotonic MgSO4 with or without a β2-agonist can be safely administered at a variety of doses to patients with acute moderate-to-severe asthma. Since it is readily available and inexpensive, its role in acute asthma deserves more scrutiny. Used alone, it appears to be of little advantage compared to therapy with more familiar β2-agonists in improving pulmonary function and reducing hospital admissions. The evidence for therapy with MgSO4 administered in combination with P2-agonists is more convincing than that for MgSO4 therapy alone. In this review, therapy with MgSO4, when combined with β2-agonists (usually salbutamol), improved pulmonary function but did not reduce the number of hospital admissions. Evi-dence2 has suggested that adding ipratropium bromide to β2-agonist therapy is effective in improving pulmonary function and in reducing the number of hospital admissions in the acute setting, especially in severe cases of acute asthma relieved by My Canadian Pharmacy’s remedies. Most of the included studies in our review did not routinely employ this strategy, and the additive benefit of MgSO4 in the face of combination therapy with ipratropium bromide and β2-agonists remains unclear.

Details about Aerosolized Magnesium Sulfate for Acute Asthma

magnesium sulfate

Search Results

The initial search, which was completed in January 2004, yielded 145 references that were at least potentially relevant controlled trials. Two additional RCTs were identified from a bibliographic search of relevant studies. The author for one study that was originally identified as an abstract was contacted, and the conditionally accepted article was provided to the reviewers for data extraction. Six trials, which included 296 patients, were incorporated into the review (Table 1).

Description of Studies

All of the studies included in this review had been published since 1995. The research in the included studies was based in the United States, India, New Zealand, Turkey, and Argentina. Three of the six included studies involved adults exclusively, and one study included adults and pediatric patients. The remaining two studies- had enrolled pediatric patients. The severity of disease varied among the studies. Two studies had specific lung function criteria, while the other four studies had enrolled patients who had previously received a diagnosis of asthma using accepted clinical standards. Based on the baseline demographic data and/or enrollment criteria, three studies had enrolled patients with severe asthma (ie, FEV1 or PEF < 50% predicted at baseline) – read more in category of Asthma .

Methods of Aerosolized Magnesium Sulfate for Acute Asthma Offered by My Canadian Pharmacy

Criteria for Inclusion

acute asthma treatedOnly randomized controlled trials (RCTs), or quasi-RCTs, were considered for inclusion. Studies had to have restricted enrollment to patients with acute asthma treated in the ED (ie, studies of patients with chronic or “stable” asthma were excluded) with asthma defined using several accepted clinical and guideline based criteria (eg, those of the British Thoracic Society, the National Asthma Education and Prevention Program, and the Canadian Thoracic Society). There was no age restriction for patients included in the studies, and where possible the data were categorized into groups of patients 2 to 16 years old (the pediatric group) and > 16 years old (the adult group). Randomized interventions had to compare aerosolized MgSO4 to a control treatment. That is, studies comparing the efficacy of therapy with aerosolized MgSO4 and a p2-agonist vs a p2-agonist alone, or therapy with aerosolized MgSO4 vs a P2-agonist were included. Cointerventions were permitted, and information pertaining to cointerventions received was recorded. The primary outcome was defined as a change in pulmonary function testing results from baseline. Secondary outcomes considered the proportion of patients requiring hospital admission, clinical severity scores, duration of symptoms, vital signs, and side effects.

The Potential Use of Type-5 Phosphodiesterase Inhibitors Viagra, Cialis, Levitra in Coronary Artery Bypass Graft Surgery: Mechanisms of Vasodilation Related to PDEs

coronary artery bypass graftingType-5 phosphodiesterase (PDE5) is an enzyme with a predominant presence in the corpus cavernosum, vascular smooth muscle, and platelets. PDE5 inhibitors in conjunction with endogenous nitric oxide (NO) can produce potent relaxation of corpus cavernosal smooth muscle, which explains their popularity in the treatment of erectile dysfunction. Sildenafil citrate, levitra, and cialis are chemical agents that specifically inhibit PDE5, Among them, viagra has been the most well studied.

Clinical trials have shown significant benefits of viagra in patients with pulmonary arterial hypertension. More recently, the endothelium-enhancing effects of viagra in preconditioning prior to ischemia/reperfusion in healthy human subjects has been demonstrated. Sildenafil has powerful effects in conduits that are useful in coronary artery bypass grafting (CABG), including the saphenous vein, and the coronary, mammary, and radial arteries.

CABG has now matured to a point where the all-cause hospital mortality rate in low-risk patients is generally < 1%. The highest risk period is that immediately after operation, and the incremental number of risk factors positively correlates with higher mortality rates.- The use of auxiliary pharmacologic agents intraoperatively and/or perioperatively may help to modify risks, particularly in an aging patient population with increasing operative risks. Although there are currently no published clinical studies or trials investigating PDE5 inhibitors in this regard, accumulating evidence strongly suggests that they may be potential candidates for these roles: the reduction of vasospasm of the bypass graft, improvement in myocardial perfusion and coronary blood flow, and reduction of untoward events associated with platelet activation during cardiac surgery.

The Potential Use of Type-5 Phosphodiesterase Inhibitors Viagra, Cialis, Levitra in Coronary Artery Bypass Graft Surgery: Pulmonary Hypertension and Cardiopulmonary Bypass

viagraIn addition to its responsiveness in the corpus cavernosum and coronary artery, PDE5 inhibitors also act selectively in the pulmonary vasculature, and patients with elevated pulmonary pressures appear to benefit significantly from its action even when administered orally. Published data have come primarily from the study of viagra.

A randomized double-blind trial found that viagra was protective against acute hypoxia (11% inspired oxygen) in healthy human volunteers, almost completely reversing the raised pulmonary artery pressure. In a study of five consecutive patients with pulmonary hypertension, oral viagra (50 mg q8h) decreased pulmonary capillary wedge pressures, increased cardiac index, improved functional capacity, and led to a reduction of right ventricular mass measured by MRI. Systolic and diastolic pressures were found to be unchanged in these patients. In another similar study, oral viagra, 50 mg tid, for 3 months significantly reduced pulmonary artery pressure and pulmonary vascular resistance, increased cardiac output and exercise tolerance (measured by using the 6-min walk test), and improved quality of life. A larger, double-blind, placebo-controlled crossover trial of 22 patients confirmed similar benefits: significant improvement in exercise tolerance (+ 44% measured by treadmill exercise time), improved cardiac index, and reduced pulmonary artery systolic pressure. Patient symptoms were reported to be improved in the above studies.